Transplantation to Treat Cancer
High-dose chemotherapy (HDC) and bone marrow or blood stem cell transplantation (SCT) are the best treatments available for many kinds of cancer. To deliver high-dose chemotherapy, stem cells must be collected before treatment for infusion into the patient to support the recovery of the patient’s bone marrow.Chemotherapy drugs and radiation therapy are used to treat cancer. Higher doses of therapy kill more cancer cells than lower doses of therapy in certain types of cancer. When higher doses of therapy kill more cancer than lower doses, doctors say there is a “dose response effect It works like this: high doses of chemo (sometimes along with radiation), work better than standard doses to kill cancer cells. But high doses can also kill all the stem cells and cause the bone marrow to completely stop making blood cells, which we need to live.